The Permanent Forum welcomes the study transmitted in the note by the Secretariat entitled “Improving the health and wellness of Indigenous Peoples globally: operationalization of Indigenous determinants of health” (E/C.19/2024/5). The Forum recognizes that the Indigenous determinants of health framework contains 33 risk and protective factors that empower United Nations entities and Member States to improve the health and wellness of Indigenous Peoples. Those entities and Member States must adopt the framework to operationalize the Indigenous determinants of health globally.